LGI1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5408-20, A5408-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 64kDa
Observed Molecular Weight: 64kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 9211
SWISS: O95970
Alternate Names: EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; LGI1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Wnt -Catenin Signaling Pathway, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: LGI1
Research Use Only