LIN28A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6034-20, A6034-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 23kDa
Observed Molecular Weight: 28kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 79727
SWISS: Q9H9Z2
Alternate Names: CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A; LIN28A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Neuroscience, Stem Cells, Embryonic Stem Cells.
NCBI Alias: LIN28A
Research Use Only