Lipocalin-2/NGAL Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3176-20, A3176-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 23kDa
Observed Molecular Weight: 22kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 3934
SWISS: P80188
Alternate Names: p25; 24p3; MSFI; NGAL; Lipocalin-2/NGAL
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Immunology Inflammation, Cardiovascular, Lipids, Fatty Acids.
NCBI Alias: LCN2
Research Use Only