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LZTS2 Rabbit pAb - A14598

LZTS2 Rabbit pAb - A14598

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LZTS2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A14598-20, A14598-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 73kDa

Observed Molecular Weight: 73kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 84445

SWISS: Q9BRK4

Alternate Names: LAPSER1; LZTS2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

NCBI Alias: LZTS2

Research Use Only