MAPT Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A23656-20, A23656-100
Citations, Manuals and MSDS Available upon request.
Background: Enables DNA binding activity; microtubule binding activity; and protein kinase binding activity. Involved in negative regulation of tubulin deacetylation; regulation of cellular response to heat; and regulation of response to DNA damage stimulus. Acts upstream of or within several processes, including adult walking behavior; generation of neurons; and transport along microtubule. Located in several cellular components, including cytoskeleton; glial cell projection; and postsynaptic density. Is expressed in several structures, including gut; nervous system; sensory organ; smooth muscle tissue; and urinary system. Used to study Alzheimer's disease. Human ortholog (s) of this gene implicated in dementia (multiple) ; neurodegenerative disease (multiple) ; progressive supranuclear palsy; and temporal lobe epilepsy. Orthologous to human MAPT (microtubule associated protein tau).
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 35-38 kDa/44 kDa/76 kDa
Observed Molecular Weight: 50-80 kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 17762
SWISS: P10637
Alternate Names: Tau; Mtapt; PHF-tau; MAPT
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: MAPT
Research Use Only