MARCH8 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12962-20, A12962-100
Citations, Manuals and MSDS Available upon request.
Background: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 33kDa
Observed Molecular Weight: 33kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 220972
SWISS: Q5T0T0
Alternate Names: MIR; CMIR; c-MIR; MARCH8; RNF178; MARCH-VIII
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Ubiquitin, Immunology Inflammation.
NCBI Alias: MARCHF8
Research Use Only