MECOM Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5674-20, A5674-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 18kDa/117kDa/118kDa/125kDa/139kDa
Observed Molecular Weight: 105kDa/145kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2122
SWISS: Q03112/Q13465
Alternate Names: EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1; MECOM
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation.
NCBI Alias: MECOM
Research Use Only