MITF Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1255-20, A1255-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 59kDa
Observed Molecular Weight: 50-70kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 4286
SWISS: O75030
Alternate Names: MI; WS2; CMM8; WS2A; COMMAD; MITF-A; bHLHe32; MITF
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Signal Transduction, MAPK-Erk Signaling Pathway, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: MITF
Research Use Only