Mitofusin 2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13606-20, A13606-100
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable several functions, including GTP binding activity; GTPase activity; and enzyme binding activity. Involved in mitochondrial fusion; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; and positive regulation of cold-induced thermogenesis. Acts upstream of or within blastocyst formation and camera-type eye morphogenesis. Located in microtubule cytoskeleton and mitochondrion. Is expressed in several structures, including brain; early conceptus; eye; heart; and oocyte. Used to study Charcot-Marie-Tooth disease type 2A2A. Human ortholog (s) of this gene implicated in Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease type 2A2A; Charcot-Marie-Tooth disease type 2A2B; and Charcot-Marie-Tooth disease type 6. Orthologous to human MFN2 (mitofusin 2).
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 68kDa/86kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 170731
Alternate Names: Fzo; D630023P19Rik; Mitofusin 2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology & Developmental Biology, Apoptosis, Autophagy, Endocrine & Metabolism, Mitochondrial metabolism, Mitochondrial markers, Mitophagy fission and fusion, Neuroscience, Neurodegenerative Diseases, Mitochondrial Control of Autophagy.
NCBI Alias: Mfn2
Research Use Only