NEDD4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0552-20, A0552-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 149kDa
Observed Molecular Weight: 120kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 4734
SWISS: P46934
Alternate Names: RPF1; NEDD4-1; NEDD4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway, Endocrine Metabolism, Mitochondrial metabolism, Immunology Inflammation, Neuroscience.
NCBI Alias: NEDD4
Research Use Only