NMNAT1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4937-20, A4937-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD) . The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 32kDa
Observed Molecular Weight: 29kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 64802
SWISS: Q9HAN9
Alternate Names: LCA9; NMNAT; PNAT1; SHILCA; NMNAT1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: NMNAT1
Research Use Only