NOS1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1485-20, A1485-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Rat
Protein Weight: 161kDa
Observed Molecular Weight: 160kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 4842
SWISS: P29475
Alternate Names: NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS; NOS1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, MAPK-Erk Signaling Pathway, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Angiogenesis.
NCBI Alias: NOS1
Research Use Only