NPC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5413-20, A5413-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 17kDa
Observed Molecular Weight: 19kDa/17-21kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 10577
SWISS: P61916
Alternate Names: HE1; EDDM1; NPC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Lipids.
NCBI Alias: NPC2
Research Use Only