NRF1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5547-20, A5547-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2) -like 1" which has an official symbol of NFE2L1.
Category: Polyclonal Antibodies
Applications: WB, ELISA, ChIP
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 54kDa
Observed Molecular Weight: 70kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 4899
SWISS: Q16656
Alternate Names: ALPHA-PAL; NRF1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 10μg-15μg of Chromatin
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Endocrine Metabolism, Mitochondrial metabolism, Nucleotide metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: NRF1
Research Use Only