PAK5 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15872-20, A15872-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 81kDa
Observed Molecular Weight: 81kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 57144
SWISS: Q9P286
Alternate Names: PAK7; PAK5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Cell Biology Developmental Biology, Apoptosis, TGF-b-Smad Signaling Pathway, Neuroscience.
NCBI Alias: PAK5
Research Use Only