PCNT Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A20161-20, A20161-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM) . The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 378kDa
Observed Molecular Weight: 251kDa/378kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5116
SWISS: O95613
Alternate Names: KEN; PCN; MOPD2; PCNT2; PCNTB; PCTN2; SCKL4; PCNT
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: PCNT
Research Use Only