PDE6B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6942-20, A6942-100
Citations, Manuals and MSDS Available upon request.
Background: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 98kDa
Observed Molecular Weight: 98kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5158
SWISS: P35913
Alternate Names: rd1; PDEB; RP40; CSNB3; CSNBAD2; GMP-PDEbeta; PDE6B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Neuroscience.
NCBI Alias: PDE6B
Research Use Only