PDE6D Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14762-20, A14762-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 17kDa
Observed Molecular Weight: 14-15kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5147
SWISS: O43924
Alternate Names: PDED; JBTS22; PDE6D
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction.
NCBI Alias: PDE6D
Research Use Only