PDK1/PDHK1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0834-20, A0834-100
Citations, Manuals and MSDS Available upon request.
Background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 49kDa
Observed Molecular Weight: 49kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 5163
SWISS: Q15118
Alternate Names: PDK1; PDK1/PDHK1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, PI3K-Akt Signaling Pathway, Endocrine Metabolism, Carbohydrate metabolism, Warburg Effect, Immunology Inflammation, T Cell Receptor Signaling Pathway, NF-kB Signaling Pathway.
NCBI Alias: PDK1
Research Use Only