PER2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13168-20, A13168-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA, ChIP
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 137kDa
Observed Molecular Weight: 136kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8864
SWISS: O15055
Alternate Names: FASPS; FASPS1; PER2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 10μg-15μg of Chromatin
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Cardiovascular, Blood.
NCBI Alias: PER2
Research Use Only