PGC1α Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11971-20, A11971-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 91kDa
Observed Molecular Weight: 91kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 10891
SWISS: Q9UBK2
Alternate Names: LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1alpha; PGC-1 (alpha) ; PGC1α
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Cancer, Signal Transduction, mTOR Signaling Pathway, Cell Biology Developmental Biology, Endocrine Metabolism, Mitochondrial metabolism, Nucleotide metabolism, AMPK Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Obesity, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Lipids, Fatty Acids.
NCBI Alias: PPARGC1A
Research Use Only