PKLR Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12084-20, A12084-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 62kDa
Observed Molecular Weight: 62kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5313
SWISS: P30613
Alternate Names: PK1; PKL; RPK; PKRL; PKLR
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Carbohydrate metabolism.
NCBI Alias: PKLR
Research Use Only