PLA2G1B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5478-20, A5478-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs) . The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 16kDa
Observed Molecular Weight: 16kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5319
SWISS: P04054
Alternate Names: PLA2; PLA2A; PPLA2; PLA2G1B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Endocrine Metabolism, Lipid Metabolism.
NCBI Alias: PLA2G1B
Research Use Only