PLP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14251-20, A14251-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 30kDa
Observed Molecular Weight: 20-25kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5354
SWISS: P60201
Alternate Names: PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20; PLP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Cell Adhesion, Neuroscience, Cell Type Marker.
NCBI Alias: PLP1
Research Use Only