POLE2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12842-20, A12842-100
Citations, Manuals and MSDS Available upon request.
Background: DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 60kDa
Observed Molecular Weight: 59kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5427
SWISS: P56282
Alternate Names: DPE2; POLE2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair.
NCBI Alias: POLE2
Research Use Only