PON1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7338-20, A7338-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 40kDa
Observed Molecular Weight: 40kDa/55kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5444
SWISS: P27169
Alternate Names: ESA; PON; MVCD5; PON1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Lipid Metabolism, Drug metabolism, Endocrine and metabolic diseases, Diabetes, Neuroscience, Neurodegenerative Diseases, Dopamine Signaling in Parkinson's Disease, Cardiovascular, Lipids.
NCBI Alias: PON1
Research Use Only