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PPFIBP1 Rabbit pAb - A16456

PPFIBP1 Rabbit pAb - A16456

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PPFIBP1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A16456-20, A16456-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 114kDa

Observed Molecular Weight: 114kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 8496

SWISS: Q86W92

Alternate Names: L2; SGT2; hSGT2; hSgt2p; NEDSMBA; PPFIBP1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction.

NCBI Alias: PPFIBP1

Research Use Only