PPOX Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6397-20, A6397-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 51kDa
Observed Molecular Weight: 51kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5498
SWISS: P50336
Alternate Names: VP; PPO; V290M; PPOX
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers.
NCBI Alias: PPOX
Research Use Only