Prolyl hydroxylase PHD1 (EGLN2) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2252-20, A2252-100
Citations, Manuals and MSDS Available upon request.
Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 44kDa
Observed Molecular Weight: 43kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 112398
SWISS: Q96KS0
Alternate Names: EIT6; PHD1; EIT-6; HPH-1; HPH-3; HIFPH1; HIF-PH1; Prolyl hydroxylase PHD1 (EGLN2)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Invasion and Metastasis, Endocrine Metabolism, Cardiovascular, Hypoxia.
NCBI Alias: EGLN2
Research Use Only