RAB7 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12784-20, A12784-100
Citations, Manuals and MSDS Available upon request.
Background: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 23kDa
Observed Molecular Weight: 23kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7879
SWISS: P51149
Alternate Names: RAB7; CMT2B; PRO2706
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, Small G proteins.
NCBI Alias: RAB7A
Research Use Only