Rad18 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5380-20, A5380-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 56kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 56852
SWISS: Q9NS91
Alternate Names: RNF73; Rad18
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Ubiquitin.
NCBI Alias: RAD18
Research Use Only