RAD51C Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12487-20, A12487-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: IF/ICC, ELISA
Cross-reactivity: Human
Protein Weight: 42kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5889
SWISS: O43502
Alternate Names: FANCO; R51H3; BROVCA3; RAD51L2; RAD51C
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair.
NCBI Alias: RAD51C
Research Use Only