RAIDD/CRADD Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1124-20, A1124-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 23kDa
Observed Molecular Weight: 22kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8738
SWISS: P78560
Alternate Names: MRT34; RAIDD; RAIDD/CRADD
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Death Receptor Signaling Pathway.
NCBI Alias: CRADD
Research Use Only