RbAp46/RBBP7 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13456-20, A13456-100
Citations, Manuals and MSDS Available upon request.
Background: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA, ChIP
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 48kDa
Observed Molecular Weight: 48kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5931
SWISS: Q16576
Alternate Names: RbAp46; RbAp46/RBBP7
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 10μg-15μg of Chromatin
Research Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling, Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: RBBP7
Research Use Only