Recombinant Human Cyclophilin B/PPIase B/PPIB Protein
Sizes: 10ug, 50ug
Catalogue Number: RP02149-10, RP02149-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Cyclophilin B/PPIase B/PPIB Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp34-Ala212) of human PPIB (Accession #P23284) fused with a 6xHis tag at the C- terminus.
Alternate Names: CYP-S1, CYPB, HEL-S-39, OI9, SCYLP, PPIB, CYP-S1, peptidylprolyl isomerase B, CYPB, HEL-S-39, OI9, SCYLP
SWISS: P23284
GeneID: 5479
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. Contact us for customized product form or formulation.
Antigen Sequence: DEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFA
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only