Recombinant Human FKBP1A/FKBP12 Protein
Sizes: 10ug, 20ug, 50ug
Catalogue Numbers: RP00051-10, RP00051-20, RP00051-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human FKBP1A/FKBP12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu108) of human FKBP12 (Accession #NP_000792.1).
Alternate Names: FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE, FKBP1A, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
SWISS: P62942
GeneID: 2280
Species: Human
Purity: ≥ 90 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.
Source: E. coli
Tag: No tag
Formulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.
Antigen Sequence: MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only