Recombinant Human IL-18R1/CD218a Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00097-10, RP00097-20, RP00097-50, RP00097-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human IL-18R1/CD218a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu20-Arg329) of human IL18R1/CD218a (Accession #NP_003846.1) fused with an Fc, 6×His tag at the C-terminus.
Alternate Names: IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP, IL18R1/IL-18 R alpha
SWISS: Q13478
GeneID: 8809
Species: Human
Purity: ≥ 85 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio-Activity: Measured by its binding ability in a functional ELISA.Immobilized IL18R1 Mouse mAb at 1μg/mL (100 μL/well) can bind Human IL18R1 with a linear range of 0.03-1.06ng/ml.
Source: HEK293 cells
Tag: C-hFc&His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: ESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTR
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only