Recombinant Human IL-2RB/CD122 Protein
Sizes: 20ug, 50ug, 100ug
Catalogue Numbers: RP00407-20, RP00407-50, RP00407-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human IL-2RB/CD122 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala27-Asp239) of human IL-2RB/CD122 (Accession #P14784) fused with a 6×His tag at the C-terminus.
Alternate Names: IL2RB, CD122, IL15RB, P70-75
SWISS: P14784
GeneID: 3560
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKD
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only