Recombinant Human PMKase/PMVK Protein
Sizes: 10ug, 50ug
Catalogue Number: RP02879LQ-10, RP02879LQ-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human PMKase/PMVK Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu192) of human PMKase/PMVK (Accession #NP_006547.1) fused with a 6×His tag at the N-terminus.
Alternate Names: PMVK, HUMPMKI, PMK, PMKA, PMKASE, POROK1
SWISS: Q15126
GeneID: 10654
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Background: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
Source: E. coli
Tag: N-His
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Antigen Sequence: MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only