Recombinant Human TIGIT Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00080-10, RP00080-20, RP00080-50, RP00080-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human TIGIT Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met22-Pro141) of human TIGIT (Accession #NP_776160.2) fused with a 6×His tag at the C-terminus.
Alternate Names: VSIG9, VSTM3, WUCAM, TIGIT
SWISS: Q495A1
GeneID: 201633
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: This protein is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The protein is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Bio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT at 1.5 μg/mL (100 μL/well) can bind Human CD155 with a linear range of 0.15-1.2 μg/mL.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only