Recombinant Mouse Alpha-Synuclein/SNCA Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00700-10, RP00700-20, RP00700-50, RP00700-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse Alpha-Synuclein/SNCA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ala140) of mouse SNCA/Alpha-Synuclein (Accession #O55042).
Alternate Names: Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloidprecursor; NACP; Snca
SWISS: O55042-1
GeneID: 20617
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB).
Source: E. coli
Tag: No tag
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Contact us for customized product form or formulation.
Antigen Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only