Recombinant Mouse PDGFR-alpha/CD140a Protein
Sizes: 10ug, 50ug
Catalogue Number: RP00718-10, RP00718-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse PDGFR-alpha/CD140a Protein is produced by Human cells expression system. The target protein is expressed with sequence (Leu25-Glu524) of mouse PDGFR-alpha/CD140a (Accession #P26618) fused with an Fc tag at the C-terminus.
Alternate Names: Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derivedgrowth factor receptor; CD140 antigen-like family member A; Platelet-derived growth factor alphareceptor; CD140a; PDGFRA
SWISS: P26618
GeneID: 18595
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of theplatelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which formeither homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomericforms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- α and - β. These two receptorisoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα,#NAMEsignaling has been linked to a number of proliferative disorders.
Source: HEK293 cells
Tag: C-Fc
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Contact us for customized product form or formulation.
Antigen Sequence: LLLPSILPNENEKIVQLNSSFSLRCVGESEVSWQHPMSEEDDPNVEIRSEENNSGLFVTVLEVVNASAAHTGWYTCYYNHTQTDESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPETQVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVKGRTFKTSEFNVYALKATSELNLEMDARQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGEYECAARQATKEVKEMKRVTISVHEKGFVEIEPTFGQLEAVNLHEVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQKSQETRYQSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELSTLVPASILDLVDDHHGSGGGQTVRCTAEGTPLPEIDWMICKHIKKCNNDTSWTVLASNVSNIITELPRRGRSTVEGRVSFAKVEETIAVRCLAKNNLSVVARELKLVAPTLRSE
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only