Recombinant Mouse Renin-1/REN1 Protein
Sizes: 10ug, 50ug
Catalogue Number: RP02135-10, RP02135-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse Renin-1/REN1 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Leu22-Arg402) of Mouse Renin-1/REN1 (Accession #P06281) fused with a 10xHis tag at the C-terminus.
Alternate Names: D19352, Ren, Ren-1, Ren-A, Ren1c, Ren1d, Rn-1, Rnr, REN1
SWISS: P06281
GeneID: 19701
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Mouse Renin, also known as Renin-1,is a member of the peptidase A1 amily. Renin is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. It cleaves angiotensinogen to generate angiotensin I, which can be further converted by angiotensin converting enzyme (ACE) to angiotensin II. Angiotensin II is the active molecule of the reninangiotensin system that acts by binding to angiotensin receptors type 1 and 2 (AT1 and AT2),and has direct pathophysiological effects on the heart and peripheral vasculature. After secretion, inactive prorenin can be proteolytically activated by trypsin, cathepsin B, or other proteinases.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only