Recombinant Mouse SLAMF2/CD48 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP01591-10, RP01591-20, RP01591-50, RP01591-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse SLAMF2/CD48 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe23-Arg216) of mouse SLAMF2/CD48 (Accession #NP_031675.1) fused with a hFc tag at the C-terminus.
Alternate Names: BCM1, BLAST, BLAST1, hCD48, mCD48, MEM-102, SLAMF2, CD48
SWISS: P18181
GeneID: 12506
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Bio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD48 (Catalog: RP01591) at 10 μg/mL (100 μL/well) can bind Human CD224 (Catalog: RP00167) with a linear range of 0.87-18.4 ng/mL.
Source: HEK293 cells
Tag: C-hFc
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Antigen Sequence: FQGHSIPDINATTGSNVTLKIHKDPLGPYKRITWLHTKNQKILEYNYNSTKTIFESEFKGRVYLEENNGALHISNVRKEDKGTYYMRVLRETENELKITLEVFDPVPKPSIEINKTEASTDSCHLRLSCEVKDQHVDYTWYESSGPFPKKSPGYVLDLIVTPQNKSTFYTCQVSNPVSSKNDTVYFTLPCDLAR
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only