RUNX1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2055-20, A2055-100
Citations, Manuals and MSDS Available upon request.
Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 49kDa
Observed Molecular Weight: 55kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 861
SWISS: Q01196
Alternate Names: AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; CBF2alpha; AML1-EVI-1; PEBP2alpha; RUNX1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:700 IHC-P, 1:50 - 1:100 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Cell Biology Developmental Biology, Neuroscience, Stem Cells, Hematopoietic Progenitors, Cardiovascular, Angiogenesis.
NCBI Alias: RUNX1
Research Use Only