RYR2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0298-20, A0298-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 565kDa
Observed Molecular Weight: 564kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 6262
SWISS: Q92736
Alternate Names: RyR; ARVC2; ARVD2; RYR-2; VTSIP; VACRDS; RYR2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 IHC-P, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling, Cardiovascular, Hypoxia, Heart, Contractility, Cardiac arrhythmias.
NCBI Alias: RYR2
Research Use Only