SERPINI1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15703-20, A15703-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 46kDa
Observed Molecular Weight: 46kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5274
SWISS: Q99574
Alternate Names: PI12; HNS-S1; HNS-S2; neuroserpin; SERPINI1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience, Cell Type Marker, Neurodegenerative Diseases, Neuron marker.
NCBI Alias: SERPINI1
Research Use Only