SETDB2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7391-20, A7391-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 82kDa
Observed Molecular Weight: 100kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 83852
SWISS: Q96T68
Alternate Names: CLLD8; CLLL8; KMT1F; C13orf4; SETDB2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones.
NCBI Alias: SETDB2
Research Use Only