SETMAR Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6738-20, A6738-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 78kDa
Observed Molecular Weight: Refer to Figures
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6419
SWISS: Q53H47
Alternate Names: Mar1; METNASE; SETMAR
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling.
NCBI Alias: SETMAR
Research Use Only