SH3BP2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10243-20, A10243-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 62kDa
Observed Molecular Weight: 75kDa/80kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6452
SWISS: P78314
Alternate Names: 3BP2; CRBM; CRPM; 3BP-2; RES4-23; SH3BP2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction.
NCBI Alias: SH3BP2
Research Use Only